Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.84 |
| ▸ | CA2 | P00918 | 11/20 | 0.84 |
| ▸ | CA9 | Q16790 | 9/20 | 0.74 |
| ▸ | CA12 | O43570 | 8/20 | 0.74 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.68 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.68 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980021 | 1.00 | CA1 (0.84) | CA1CA2CA9CA12PTPN7 | |
| SCHEMBL18606699 | 0.86 | CA1 (0.76) | CA1CA2CA9PTPN7MEN1 | |
| SCHEMBL9280164 | 0.85 | PTPN7 (1.00) | CA1CA2CA9CA12PTPN7 | |
| SCHEMBL15214321 | 0.84 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL822378 | 0.84 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL14580374 | 0.84 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12310125 | 0.84 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL27181403 | 0.84 | RAB9A (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL8421687 | 0.84 | CA2 (0.84) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL95883 | 0.84 | CA2 (0.84) | CA1CA2CA9CA12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775110-B1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | EP | claimed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | claimed |
| CN-1114402-C | Isothiazolones | WARNER LAMBERT CO (US) | 2003-07-16 | — | — | CN | disclosed |
| CN-1185737-A | Isothiazolones | WARNER LAMBERT CO (US) | 1998-06-24 | — | — | CN | disclosed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |