Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227024 | 0.92 | SLC6A4 (0.42) | SLC6A4MAPTSMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL6671646 | 0.91 | DDR1 (0.38) | SLC6A4SMN1; SMN2SLC6A2SLC6A3MEN1 | |
| SCHEMBL6668436 | 0.89 | KMT2A (0.51) | SLC6A4MAPTSLC6A2SLC6A3MEN1 | |
| SCHEMBL6229113 | 0.87 | HTR1A (0.35) | SLC6A4MAPTSMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL4353992 | 0.87 | KMT2A (0.40) | SLC6A4MAPTSMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL6227136 | 0.86 | LMNA (0.39) | SLC6A4MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL6227969 | 0.86 | SLC6A4 (0.46) | SLC6A4SMN1; SMN2SLC6A2SLC6A3MEN1 | |
| SCHEMBL6227046 | 0.85 | MAPT (0.41) | MAPTSMN1; SMN2MEN1KMT2ACYP2D6 | |
| SCHEMBL6229825 | 0.84 | ITGB2 (0.38) | SLC6A4MAPTSLC6A2MEN1POLB | |
| SCHEMBL6225098 | 0.83 | MAPT (0.40) | SLC6A4MAPTSMN1; SMN2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |