Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227024 | 0.94 | SLC6A4 (0.42) | DDR1SMN1; SMN2L3MBTL1MAPK1SLC6A4 | |
| SCHEMBL6227969 | 0.92 | SLC6A4 (0.46) | DDR1SMN1; SMN2L3MBTL1MAPK1SLC6A4 | |
| SCHEMBL6225937 | 0.91 | SLC6A4 (0.38) | SMN1; SMN2SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL6229113 | 0.89 | HTR1A (0.35) | SMN1; SMN2L3MBTL1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6668436 | 0.88 | KMT2A (0.51) | L3MBTL1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL6229825 | 0.88 | ITGB2 (0.38) | L3MBTL1MAPK1SLC6A4SLC6A2MEN1 | |
| SCHEMBL6227046 | 0.87 | MAPT (0.41) | SMN1; SMN2L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL6227136 | 0.86 | LMNA (0.39) | SMN1; SMN2L3MBTL1MAPK1SLC6A4LMNA | |
| SCHEMBL4359272 | 0.85 | GAA (0.42) | DDR1SMN1; SMN2L3MBTL1MAPK1SLC6A4 | |
| SCHEMBL6225665 | 0.82 | MEN1 (0.38) | L3MBTL1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |