Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221389 | 0.86 | RAB9A (0.44) | HSD17B10KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6224673 | 0.83 | ALDH1A1 (0.44) | KMT2AMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6224808 | 0.81 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1MEN1POLB | |
| SCHEMBL4369750 | 0.81 | ALPL (0.44) | RAB9ASMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL15946999 | 0.78 | ADORA2A (0.49) | KMT2AMAPTRAB9AALDH1A1POLB | |
| SCHEMBL30395005 | 0.75 | ADORA2A (0.47) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10405791 | 0.72 | HSD17B10 (0.72) | HSD17B10KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL6224124 | 0.72 | HTT (0.47) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6224141 | 0.71 | HTT (0.44) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19814272 | 0.70 | NOTUM (0.53) | HSD17B10KMT2AMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186598-B1 | Process of preparing 5-(2-substituted-4-nitrophenyl)-oxazole, oxazole compound, and process of preparing the same | NIPPON SYNTHETIC CHEM IND (JP) | 2005-03-16 | — | — | EP | disclosed |
| US-6423849-B1 | VIRICIDES; ANTICANCER AGENTS | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| US-20020035265-A1 | Process of preparing 5-(2-substituted-4-nitrophenyl)-oxazole, novel oxazole compound, and process of preparing the same | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. | 2002-03-21 | — | — | US | disclosed |
| EP-1186598-A1 | Process of preparing 5-(2-substituted-4-nitrophenyl)-oxazole, oxazole compound, and process of preparing the same | The Nippon Synthetic Chemical Industry Co., Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035265-A1 | Process of preparing 5-(2-substituted-4-nitrophenyl)-oxazole, novel oxazole compound, and process of preparing the same | PNPO, OXA1L, ATIC | HSD17B10 3233/4885KMT2A 1395/4885MAPT 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.