Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787614 | 0.85 | LMNA (0.41) | LMNA | |
| SCHEMBL7588474 | 0.84 | LMNA (0.34) | LMNA | |
| SCHEMBL9787561 | 0.82 | LMNA (0.37) | LMNA | |
| SCHEMBL621486 | 0.80 | TPMT (0.33) | LMNACYP1A2 | |
| SCHEMBL377437 | 0.80 | TPMT (0.33) | LMNACYP1A2 | |
| SCHEMBL6397169 | 0.78 | KDM4E (0.32) | LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL620189 | 0.78 | KDM4E (0.32) | LMNACYP1A2 | |
| SCHEMBL6389935 | 0.78 | KDM4E (0.32) | LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28391599 | 0.78 | KDM4E (0.32) | LMNACYP1A2 | |
| SCHEMBL11220028 | 0.78 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175392-B1 | CONTRAST MEDIA | AMERSHAM HEALTH AS (NO) | 2005-06-22 | — | — | EP | disclosed |
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| EP-1175392-A1 | CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 2002-01-30 | — | — | EP | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| WO-2000066544-A1 | CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 2000-11-09 | — | — | WO | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |
| US-5047228-A | X-ray contrast; medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4225577-A | Ionic polyiodo benzene derivatives useful as X-ray contrast media | GUERBET S.A. (FR) | 1980-09-30 | — | — | US | disclosed |