Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19491268 | 0.84 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL18700890 | 0.78 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL18707079 | 0.76 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL18706997 | 0.75 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL13122520 | 0.72 | — | — | |
| SCHEMBL1807941 | 0.72 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL30609094 | 0.70 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL23119101 | 0.69 | — | — | |
| SCHEMBL20644808 | 0.69 | — | — | |
| SCHEMBL21311921 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130295019-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI (US) | 2013-11-07 | — | — | US | claimed |
| WO-2012021390-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-02-16 | — | — | WO | claimed |
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-11-09 | — | — | US | disclosed |
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-24 | — | — | US | disclosed |
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-24 | — | — | US | disclosed |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-09-01 | — | — | US | disclosed |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-09-01 | — | — | US | disclosed |
| US-9809560-B2 | Ligands and methods for labeling biomolecules in vivo | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809560-B2 | Ligands and methods for labeling biomolecules in vivo | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809560-B2 | Ligands and methods for labeling biomolecules in vivo | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCACATION (US) | 2017-10-19 | — | — | US | disclosed |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCACATION (US) | 2017-10-19 | — | — | US | disclosed |
| US-20130295019-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130295019-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130295019-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI (US) | 2013-11-07 | — | — | US | disclosed |
| WO-2012021390-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | MEN1 3749/4885KMT2A 914/4885THRB 1961/4885 |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | MEN1 3749/4885KMT2A 914/4885THRB 1961/4885 |
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | MEN1 3749/4885KMT2A 914/4885THRB 1961/4885 |
| US-20130295019-A1 | LIGANDS AND METHODS FOR LABELING BIOMOLECULES IN VIVO | FABP1, TK1, FABP7 | MEN1 2482/4885KMT2A 3388/4885THRB 146/4885 |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | MEN1 3749/4885KMT2A 914/4885THRB 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.