Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498104 | 0.81 | L3MBTL1 (0.46) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL1793005 | 0.81 | L3MBTL1 (0.46) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6600350 | 0.79 | L3MBTL1 (0.45) | POLBKMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL28680129 | 0.74 | POLB (0.54) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7760631 | 0.71 | MEN1 (0.47) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL12822665 | 0.71 | POLB (0.51) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL6629689 | 0.70 | SIGMAR1 (0.53) | ALDH1A1MAPTHPGDCYP1A2CYP3A4 | |
| SCHEMBL20893429 | 0.70 | ALDH1A1 (0.48) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL2724212 | 0.69 | ALDH1A1 (0.54) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL29244104 | 0.69 | KMT2A (0.46) | POLBKMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793380-A | Naphthoquinones of 2,3 2 third sulfone of epoxy, 5,8 dimethoxy 1,4 and preparation method thereof and the medicine containing it | 黑龙江八农垦大学 | 2018-03-13 | — | — | CN | claimed |
| CN-110891980-B | Radical polymerization control agent and radical polymerization control method | 川崎化成工业株式会社 | 2022-09-30 | — | — | CN | disclosed |
| CN-110891980-A | Radical polymerization control agent and radical polymerization control method | 川崎化成工业株式会社 | 2020-03-17 | — | — | CN | disclosed |
| US-20180116977-A1 | NOVEL TREATMENT OF PROSTATE CARCINOMA | PELLFICURE PHARMACEUTICALS, INC. | 2018-05-03 | — | — | US | disclosed |
| CN-107793380-A | Naphthoquinones of 2,3 2 third sulfone of epoxy, 5,8 dimethoxy 1,4 and preparation method thereof and the medicine containing it | 黑龙江八农垦大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-107759538-A | Naphthoquinones of 2,3 epoxy, 2 nonyl sulfone, 5,8 dimethoxy 1,4 and preparation method thereof and the medicine containing it | 黑龙江八农垦大学 | 2018-03-06 | — | — | CN | disclosed |
| CN-103124563-A | Combination Therapy for Prostate Cancer Treatment | PELLFICURE PHARMACEUTICALS INC | 2013-05-29 | — | — | CN | disclosed |
| EP-1552836-A1 | ANTI-NEURODEGENERATIVE AGENTS | Ikeda, Joh-E (JP) | 2005-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116977-A1 | NOVEL TREATMENT OF PROSTATE CARCINOMA | KLK3, AR, PLK1 | POLB 986/4885KMT2A 2336/4885MEN1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.