SCHEMBL6228367

SCHEMBL6228367

[CH2]C12CC3CC(C(=O)O)(C1)CC(C(=O)O)(C3)C2

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6226952 0.87 HSD11B1 (0.35) PKML3MBTL1ALDH1A1
SCHEMBL6229200 0.86 ALDH1A1 (0.34) ALDH1A1KMT2A
SCHEMBL282760 0.86 PKM (0.42) PKML3MBTL1ALDH1A1SMN1; SMN2LMNA
SCHEMBL6228514 0.85 MEN1 (0.45) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL4580832 0.84 PKM (0.46) PKML3MBTL1ALDH1A1SMN1; SMN2LMNA
SCHEMBL6228385 0.82 ALDH1A1 (0.40) PKML3MBTL1ALDH1A1
SCHEMBL6227784 0.81
SCHEMBL5176912 0.81 L3MBTL1 (0.50) PKML3MBTL1ALDH1A1SMN1; SMN2LMNA
SCHEMBL4037130 0.76 GLA (0.36) L3MBTL1ALDH1A1SMN1; SMN2LMNAMEN1
SCHEMBL1732678 0.76 HSD11B1 (0.41) PKML3MBTL1ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602975-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-12-07 EP disclosed