Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829088 | 0.85 | CYP1A2 (0.38) | HNF4AFFAR1PTGS1PTGS2ADRA2B | |
| SCHEMBL541999 | 0.82 | HNF4A (0.43) | HNF4AFFAR1PTGS1PTGS2ADRA2B | |
| SCHEMBL2830780 | 0.81 | MAP2K1 (0.48) | HNF4AALDH1A1TTRMAP2K1MEN1 | |
| SCHEMBL2747715 | 0.80 | F2 (0.44) | HNF4AFFAR1PTGS1PTGS2ADRA2B | |
| Hydrochloric Acid SCHEMBL6732842 | 0.80 | HNF4A (0.42) | HNF4AFFAR1PTGS1PTGS2ADRA2B | |
| Hydrochloric Acid SCHEMBL7951893 | 0.79 | MAP2K1 (0.47) | HNF4ATTRMAP2K1HTTKMT2A | |
| SCHEMBL689828 | 0.78 | HNF4A (0.41) | HNF4AFFAR1PTGS1PTGS2ADRA2B | |
| SCHEMBL2536166 | 0.78 | HNF4A (0.62) | HNF4APTGS2ALDH1A1ALOX15MEN1 | |
| SCHEMBL1783561 | 0.77 | ALDH1A1 (0.57) | HNF4AALDH1A1AKR1C2AKR1C1MEN1 | |
| SCHEMBL22637148 | 0.77 | KDM4E (0.57) | HNF4AFFAR1PTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080368-B1 | MOLECULAR ROD AND USES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6403705-B1 | POLYPHENYENEVINYLENES FUNCTIONALIZED BY GROUPS WITH A VERY STRONG AFFINITY FOR BIOLOGICAL MACROMOLECULES; SPIRAL CRYSTALLIZATION | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2002-06-11 | — | — | US | disclosed |
| EP-1080368-A1 | MOLECULAR ROD AND USES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999061912-A1 | MOLECULAR ROD AND USES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1999-12-02 | — | — | WO | disclosed |