SCHEMBL541999

SCHEMBL541999

C#Cc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.43
HSD17B10 Q99714 2/20 0.42
CDC25A P30304 1/20 0.42
CDC25B P30305 1/20 0.42
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 1/20 0.42
CYP1A2 P05177 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41
GRM4 Q14833 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6732842 0.98 HNF4A (0.42) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL2620550 0.88 ALDH1A1 (0.41) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL17529586 0.88 PARP1 (0.42) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL12855671 0.85 CLCN2 (0.38) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL2747715 0.85 F2 (0.44) HNF4AHSD17B10ALDH1A1ALOX15CYP1A2
SCHEMBL2745941 0.85 CYP1A2 (0.41) HNF4AALDH1A1ALOX15CYP1A2TDP1
SCHEMBL18957988 0.84 NEU3 (0.43) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL14094994 0.84 NEU3 (0.43) HNF4AHSD17B10CDC25ACDC25BALDH1A1
SCHEMBL13926880 0.83 ALDH1A1 (0.51) ALDH1A1CYP1A2TDP1MEN1KMT2A
SCHEMBL13926957 0.83 ALDH1A1 (0.47) ALDH1A1CYP1A2TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4013650-A None JP disclosed
US-12145918-B2 Crosslinkable mesogenic dianhydride monomers UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2024-11-19 US disclosed
US-20240101525-A1 Crosslinkable Mesogenic Dianhydride Monomers THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2024-03-28 US disclosed
WO-2023219075-A1 METHOD FOR MANUFACTURING SUBSTRATE EQUIPPED WITH WEAK ANCHORING ALIGNMENT FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-11-16 WO disclosed
WO-2023157876-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-08-24 WO disclosed
WO-2023068084-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL DISPLAY ELEMENT, COMPOUND AND POLYMER 日産化学株式会社 2023-04-27 WO disclosed
WO-2023068085-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL DISPLAY ELEMENT, AND COMPOUND 日産化学株式会社 2023-04-27 WO disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
WO-2022107545-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-05-27 WO disclosed
CN-1231525-C Material for insulating film, varnish for insulating film, and semiconductor device using the same SUMITOMO BAKELITE CO (JP) 2005-12-14 CN disclosed
CN-1229422-C Heat-resistant resin precursor, heat-resistant resin, insulating film and semiconductr device SUMITOMO DAKELITE CO LTD (JP) 2005-11-30 CN disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
CN-1462289-A Heat-resistant resin precursor, heat-resistant resin, insulating film and semiconductr device SUMITOMO DAKELITE CO LTD (JP) 2003-12-17 CN disclosed
CN-1461323-A Material for insulating film, coating varnish for insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE CO (JP) 2003-12-10 CN disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed
JP-H0413650-A DIPHENYLDIACETYLENIC TETRACARBOXYLIC ACID ESTER ASAHI CHEM IND CO LTD 1992-01-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 HNF4A 744/4885HSD17B10 1255/4885CDC25A 1934/4885
US-12145918-B2 Crosslinkable mesogenic dianhydride monomers DIAPH1, MAP1LC3C, MAP1LC3A HNF4A 3634/4885HSD17B10 1869/4885CDC25A 869/4885
US-20240101525-A1 Crosslinkable Mesogenic Dianhydride Monomers DIAPH1, MAP1LC3C, MAP1LC3A HNF4A 3634/4885HSD17B10 1869/4885CDC25A 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.