Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.31 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230609 | 0.83 | ABHD6 (0.36) | TRAP1HSP90B1 | |
| SCHEMBL6232130 | 0.80 | TRAP1 (0.38) | DPP8DPP4DPP9DPP7HSP90AA1 | |
| SCHEMBL6229458 | 0.79 | DPP8 (0.51) | DPP8DPP4DPP9DPP7HSP90AA1 | |
| SCHEMBL15893724 | 0.75 | ESR2 (0.48) | — | |
| SCHEMBL6230180 | 0.75 | TRAP1 (0.44) | DPP8DPP4DPP9DPP7TRAP1 | |
| SCHEMBL6227541 | 0.74 | DPP4 (0.35) | DPP8DPP4DPP9DPP7CACNA1H | |
| SCHEMBL5068829 | 0.73 | NOTUM (0.52) | DPP8DPP4DPP9DPP7HSP90AA1 | |
| SCHEMBL6230084 | 0.71 | SMO (0.33) | DPP4CYP1A2CHRM4DPP7CACNA1H | |
| SCHEMBL6231874 | 0.70 | DPP8 (0.54) | DPP8DPP4DPP9DPP7TRAP1 | |
| SCHEMBL6229281 | 0.70 | CYP1A2 (0.32) | CYP1A2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |