Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL820407 | 0.76 | PGR (0.36) | METAP1 | |
| Hydrochloric Acid SCHEMBL2481792 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7581936 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7201177 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7197430 | 0.73 | CA1 (0.37) | METAP1 | |
| Hydrochloric Acid SCHEMBL7534922 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6559809 | 0.72 | METAP1 (0.31) | METAP1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL2484389 | 0.72 | PNMT (0.33) | — | |
| Hydrochloric Acid SCHEMBL816276 | 0.72 | PNMT (0.33) | — | |
| Hydrochloric Acid SCHEMBL2481590 | 0.72 | PNMT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465879-B1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | MITSUI CHEMICALS INC (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-2511305-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-2465878-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| EP-2465879-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| EP-1548018-A1 | CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME | Mitsui Chemicals, Inc. (JP) | 2005-06-29 | — | — | EP | disclosed |