Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306599 | 0.83 | PGR (0.38) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL2175208 | 0.79 | PGR (0.38) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL10841242 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL10840261 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL30873826 | 0.75 | PGR (0.42) | PGRARCA12CA9 | |
| SCHEMBL22411407 | 0.75 | PGR (0.42) | PGRARCA12CA9 | |
| SCHEMBL10838748 | 0.75 | PGR (0.47) | ALDH1A1HPGDMAPTHSD17B10PGR | |
| SCHEMBL18462587 | 0.74 | MAPT (0.44) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL30873886 | 0.74 | CA12 (0.38) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL16621405 | 0.74 | CA12 (0.38) | ALDH1A1KDM4EHPGDMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941872-A2 | Rubber composition reinforced with silica and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0080409-B1 | FLEXIBLE ELASTOMER COMPOSITION OF EPICHLOROHYDRINE | Commissariat à l'Energie Atomique (FR) | 1986-02-26 | — | — | EP | claimed |
| US-4414343-A | Epichlorohydrin-based flexible elastomer composition | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1983-11-08 | — | — | US | claimed |
| WO-2020185738-A1 | HETEROAROMATIC AND HETEROBICYCLIC AROMATIC DERIVATIVES FOR THE TREATMENT OF FERROPTOSIS-RELATED DISORDERS | COLLABORATIVE MEDICINAL DEVELOPMENT, LLC (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2013009851-A2 | OXIDATION RESISTANT BIOPROSTHETIC TISSUES AND PREPARATION THEREOF | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2013-01-17 | — | — | WO | disclosed |
| EP-1438318-B1 | TISSUE SPECIFIC FLUORESCENT CHELATES | UNIV TEXAS TECH (US) | 2005-11-09 | — | — | EP | disclosed |
| US-6962690-B2 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-08 | — | — | US | disclosed |
| EP-1438318-A1 | TISSUE SPECIFIC FLUORESCENT CHELATES | Texas Tech University (US) | 2004-07-21 | — | — | EP | disclosed |
| EP-0941872-B1 | Rubber composition reinforced with silica and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 2003-08-06 | — | — | EP | disclosed |
| US-20030099598-A1 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DOW GLOBAL TECHNOLOGIES INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003035655-A1 | TISSUE SPECIFIC FLUORESCENT CHELATES | TEXAS TECH UNIVERSITY (US) | 2003-05-01 | — | — | WO | disclosed |
| US-6053226-A | BLENDING A DIENE BASED ELASTOMER, A REINFROCEMENT FILLER COMPRISED OF PRECIPITATED SILICA AND CARBON BLACK, A PREFORMED COMPOSITE OF MICROCRYSTALLINE WAX, SILICA COUPLING AGENT, ANTIDEGRADANT, VULCANIZATION PROMOTER AND CARBON BLACK | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-25 | — | — | US | disclosed |
| EP-0941872-A2 | Rubber composition reinforced with silica and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5354729-A | Controlling weeds at low dosage; nonphytotoxic | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0579469-A2 | N-acyldihydroquinoline derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0198264-A2 | Carbamoyl imidazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-10-22 | — | — | EP | disclosed |
| US-4414343-A | Epichlorohydrin-based flexible elastomer composition | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1983-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030099598-A1 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DDB1, TNNC1, TRPC1 | ALDH1A1 2607/4885KDM4E 3823/4885HPGD 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.