Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239778 | 0.91 | BCHE (0.65) | KMT2ASMN1; SMN2MEN1SLC2A1LMNA | |
| SCHEMBL6233816 | 0.89 | SLC2A1 (0.51) | KMT2ASMN1; SMN2MEN1GAASLC2A1 | |
| SCHEMBL6233694 | 0.87 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2MEN1GAASLC2A1 | |
| SCHEMBL6235952 | 0.82 | PDCD1 (0.51) | KMT2ASMN1; SMN2MEN1GAASLC2A1 | |
| SCHEMBL6240567 | 0.82 | BCHE (0.64) | KMT2AMEN1BCHE | |
| SCHEMBL6235980 | 0.81 | SMN1; SMN2 (0.59) | KMT2ASMN1; SMN2MEN1LMNABCHE | |
| SCHEMBL6235480 | 0.81 | BCHE (0.53) | KMT2ASMN1; SMN2MEN1LMNABCHE | |
| SCHEMBL6230153 | 0.78 | MEN1 (0.51) | KMT2ASMN1; SMN2MEN1GAASLC2A1 | |
| SCHEMBL6232051 | 0.78 | MEN1 (0.51) | KMT2ASMN1; SMN2MEN1GAASLC2A1 | |
| SCHEMBL6236888 | 0.77 | SMN1; SMN2 (0.55) | KMT2ASMN1; SMN2MEN1LMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |