Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 12/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239778 | 0.88 | BCHE (0.65) | SMN1; SMN2KMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL6233779 | 0.84 | CD274 (0.49) | SMN1; SMN2KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL6230537 | 0.82 | BCHE (0.52) | SMN1; SMN2KMT2AMEN1BCHELMNA | |
| SCHEMBL6233816 | 0.82 | SLC2A1 (0.51) | SMN1; SMN2KMT2AALDH1A1MEN1BCHE | |
| SCHEMBL6230157 | 0.81 | KMT2A (0.58) | SMN1; SMN2KMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL6240567 | 0.81 | BCHE (0.64) | KMT2AMEN1MAPK1BCHE | |
| SCHEMBL6233694 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL6235480 | 0.79 | BCHE (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1BCHE | |
| SCHEMBL6235977 | 0.77 | KMT2A (0.57) | SMN1; SMN2KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL6235952 | 0.76 | PDCD1 (0.51) | SMN1; SMN2KMT2AALDH1A1MEN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |