SCHEMBL6235480

SCHEMBL6235480

COc1cccc(COc2ccc(CNCCc3ncc(C)s3)cc2OC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 6/20 0.53
NLRP3 Q96P20 1/20 0.52
PLK1 P53350 1/20 0.51
MTNR1A P48039 1/20 0.51
MTNR1B P49286 1/20 0.51
ABCB1 P08183 1/20 0.48
HTR1A P08908 2/20 0.48
HTR7 P34969 1/20 0.48
HTR6 P50406 1/20 0.48
LMNA P02545 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KMT2A Q03164 2/20 0.48
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
ALDH1A1 P00352 1/20 0.47
MEN1 O00255 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
HTR2A P28223 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6239778 0.90 BCHE (0.65) BCHENLRP3PLK1HTR1AHTR7
SCHEMBL6236888 0.85 SMN1; SMN2 (0.55) BCHENLRP3PLK1HTR1AHTR7
SCHEMBL6230157 0.81 KMT2A (0.58) BCHENLRP3PLK1HTR1AHTR7
SCHEMBL6236911 0.80 PLK1 (0.48) BCHENLRP3PLK1HTR1AHTR7
SCHEMBL6233816 0.80 SLC2A1 (0.51) BCHENLRP3HTR1AHTR7HTR6
SCHEMBL6235980 0.79 SMN1; SMN2 (0.59) BCHENLRP3HTR1AHTR7HTR6
SCHEMBL6276107 0.79 MTNR1A (0.46) MTNR1AMTNR1BABCB1HTR1ALMNA
SCHEMBL6235475 0.79 MTNR1A (0.46) MTNR1AMTNR1BABCB1HTR1ALMNA
SCHEMBL6233694 0.78 SMN1; SMN2 (0.53) BCHENLRP3PLK1HTR1AHTR7
SCHEMBL6233017 0.78 BCHE (0.50) BCHELMNAKDM4EHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005000309-A2 CHEMICAL COMPOUNDS IONIX PHARMACEUTICALS LIMITED (GB) 2005-01-06 WO disclosed