Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232051 | 1.00 | MEN1 (0.51) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL6231703 | 0.91 | LMNA (0.53) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6231706 | 0.91 | LMNA (0.53) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6233814 | 0.89 | FFAR4 (0.45) | MEN1KMT2ALMNATDP1SLC2A1 | |
| SCHEMBL6233811 | 0.87 | HTR7 (0.41) | MEN1KMT2AATMSMN1; SMN2LMNA | |
| SCHEMBL6233689 | 0.87 | CD274 (0.45) | MEN1KMT2AATMSMN1; SMN2LMNA | |
| SCHEMBL6233809 | 0.87 | HTR7 (0.41) | MEN1KMT2AATMSMN1; SMN2LMNA | |
| SCHEMBL6235950 | 0.82 | PDCD1 (0.49) | MEN1KMT2AMAPTPOLB | |
| SCHEMBL6237847 | 0.82 | BCHE (0.54) | MEN1KMT2APOLBMAPK1 | |
| SCHEMBL6237852 | 0.82 | BCHE (0.54) | MEN1KMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |