Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623932 | 0.78 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL625958 | 0.64 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL17851358 | 0.64 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL17315425 | 0.64 | LDHA (0.52) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL10083553 | 0.63 | KDM4E (0.51) | SMN1; SMN2KDM4EPOLBALDH1A1GAA | |
| SCHEMBL12503485 | 0.62 | LRRK2 (0.42) | SMN1; SMN2KMT2ARXFP1 | |
| SCHEMBL17851347 | 0.62 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2LDHAMAPT | |
| SCHEMBL6542853 | 0.62 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8574737 | 0.61 | DYRK1A (0.62) | NPC1RAB9ASMN1; SMN2KDM4ELDHA | |
| SCHEMBL3733426 | 0.61 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2KDM4ELDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |