Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LDHA | P00338 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625958 | 0.80 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2KDM4EGLA | |
| SCHEMBL624357 | 0.78 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL623071 | 0.78 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2KDM4EGLA | |
| SCHEMBL12503555 | 0.78 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2KDM4EGLA | |
| SCHEMBL627181 | 0.76 | ROCK2 (0.54) | RAB9ANPC1 | |
| SCHEMBL625756 | 0.74 | CHRM4 (0.52) | RAB9ANPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL10083553 | 0.73 | KDM4E (0.51) | SMN1; SMN2KDM4EGAAPOLBALDH1A1 | |
| SCHEMBL623924 | 0.73 | ABL1 (0.56) | ALDH1A1MAPTHTT | |
| SCHEMBL625959 | 0.72 | HDAC6 (0.46) | RAB9ANPC1SMN1; SMN2KDM4EGAA | |
| SCHEMBL17315425 | 0.72 | LDHA (0.52) | RAB9ANPC1SMN1; SMN2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |