Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503555 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL625901 | 0.84 | NPC1 (0.57) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL625106 | 0.80 | RAB9A (0.48) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL623932 | 0.80 | RAB9A (0.59) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL625028 | 0.80 | DYRK1A (0.52) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL10083543 | 0.79 | MCHR1 (0.47) | GAA | |
| SCHEMBL623943 | 0.78 | MEN1 (0.51) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 | |
| SCHEMBL10083554 | 0.78 | KMT2A (0.44) | POLBALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL10083535 | 0.77 | DDX3X (0.49) | MAPTKMT2AMEN1 | |
| SCHEMBL624218 | 0.77 | KCNMA1 (0.53) | SMN1; SMN2POLBALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |