Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622609 | 0.84 | CFTR (0.50) | CFTRIRAK4ALDH1A1PKMMAPT | |
| SCHEMBL6230911 | 0.81 | MAPT (0.50) | IRAK4ALDH1A1PKMMAPTMEN1 | |
| SCHEMBL6233612 | 0.80 | IRAK4 (0.48) | IRAK4ALDH1A1PKMMAPTMEN1 | |
| SCHEMBL17487374 | 0.74 | MAPT (0.53) | PKMMAPTMEN1KMT2ALMNA | |
| SCHEMBL6265827 | 0.74 | OPRM1 (0.42) | IRAK4ALDH1A1PKMMAPTMEN1 | |
| SCHEMBL626382 | 0.73 | MEN1 (0.50) | CFTRIRAK4ALDH1A1MAPTMEN1 | |
| SCHEMBL17417874 | 0.73 | MAPT (0.56) | CFTRIRAK4ALDH1A1MAPTMEN1 | |
| SCHEMBL6277473 | 0.72 | MAPT (0.47) | IRAK4ALDH1A1PKMMAPTMEN1 | |
| SCHEMBL6275418 | 0.71 | RAB9A (0.47) | IRAK4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL19911534 | 0.70 | ALDH1A1 (0.44) | CFTRIRAK4ALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |