Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CLTC | Q00610 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230765 | 0.89 | TERT (0.72) | TERTSTAT3HIF1ACLTC | |
| Iodide SCHEMBL6233553 | 0.84 | TERT (0.69) | TERTSTAT3HIF1AMEN1RGS12 | |
| Iodide SCHEMBL6231025 | 0.82 | TERT (0.68) | TERTSTAT3HIF1AMEN1RGS12 | |
| SCHEMBL21367403 | 0.74 | TERT (1.00) | TERTSTAT3HIF1AMEN1RGS12 | |
| SCHEMBL12486311 | 0.73 | CHRM2 (0.56) | MEN1KMT2A | |
| Iodide SCHEMBL6233141 | 0.72 | TERT (0.97) | TERTSTAT3HIF1AMEN1RGS12 | |
| SCHEMBL10023986 | 0.72 | TERT (0.88) | TERTSTAT3HIF1AMEN1RGS12 | |
| Tetrylammonium SCHEMBL1815475 | 0.72 | PSIP1 (0.50) | HIF1ACA12CA1CA2CA9 | |
| Iodide SCHEMBL6234517 | 0.71 | TERT (0.94) | TERTSTAT3HIF1AMEN1RGS12 | |
| SCHEMBL12802773 | 0.71 | LMNA (0.49) | MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027879-B1 | Use of cationic condensed polycyclic compounds for dyeing of keratinic substances, dyeing compositions and process | OREAL (FR) | 2005-04-20 | — | — | EP | claimed |
| US-6391062-B1 | APPLYING A DIRECT DYE TO HAIR WITH BENZ(DE)ISOQUINOLINE ACID SALT COMPOUND | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | claimed |
| US-6391062-B1 | APPLYING A DIRECT DYE TO HAIR WITH BENZ(DE)ISOQUINOLINE ACID SALT COMPOUND | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | disclosed |