Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAS1 | P04201 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231352 | 1.00 | PTGDR2 (0.36) | PTGDR2LMNAGAAALDH1A1NPSR1 | |
| SCHEMBL7614742 | 0.88 | GP6 (0.39) | MAS1AGTR1AGTR2GP6 | |
| SCHEMBL7614735 | 0.88 | GP6 (0.39) | MAS1AGTR1AGTR2GP6 | |
| SCHEMBL6229258 | 0.83 | PTGDR2 (0.39) | PTGDR2LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL7652319 | 0.82 | TP53 (0.38) | GAASMN1; SMN2TP53MAS1GP6 | |
| SCHEMBL7652327 | 0.82 | TP53 (0.38) | GAASMN1; SMN2TP53MAS1GP6 | |
| SCHEMBL6230300 | 0.81 | LMNA (0.35) | LMNAGAAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6230301 | 0.81 | LMNA (0.35) | LMNAGAAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL7262643 | 0.78 | PTGDR2 (0.36) | PTGDR2LMNAALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL11160756 | 0.74 | ALDH1A1 (0.51) | LMNAGAAALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076651-B1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6573288-B1 | Compounds are inhibitors of the sodium-dependent bicarbonate/chloride ion exchanger which can be used as medicines for the prophylaxis or treatment of a wide range of diseases, for example the treatment and/or prophylaxis of | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-06-03 | — | — | US | disclosed |
| EP-1076651-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999057102-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-11 | — | — | WO | disclosed |