Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609835 | 0.86 | GP6 (0.42) | ALDH1A1SMN1; SMN2AGTR2 | |
| SCHEMBL7262643 | 0.84 | PTGDR2 (0.36) | PTGDR2ALDH1A1SMN1; SMN2LMNARECQL | |
| SCHEMBL6231352 | 0.83 | PTGDR2 (0.36) | PTGDR2ALDH1A1SMN1; SMN2LMNADHFR | |
| SCHEMBL6231353 | 0.83 | PTGDR2 (0.36) | PTGDR2ALDH1A1SMN1; SMN2LMNADHFR | |
| SCHEMBL11160756 | 0.80 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNARECQLRAB9A | |
| SCHEMBL11097622 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNARECQLRAB9A | |
| SCHEMBL7648058 | 0.78 | TP53 (0.42) | SMN1; SMN2TP53 | |
| SCHEMBL6229212 | 0.78 | CA1 (0.38) | ALDH1A1SMN1; SMN2CA2CA1CA12 | |
| SCHEMBL6202033 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNARECQLRAB9A | |
| SCHEMBL5174986 | 0.76 | AGTR1 (0.39) | PTGDR2ALDH1A1SMN1; SMN2PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076651-B1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6573288-B1 | Compounds are inhibitors of the sodium-dependent bicarbonate/chloride ion exchanger which can be used as medicines for the prophylaxis or treatment of a wide range of diseases, for example the treatment and/or prophylaxis of | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-06-03 | — | — | US | disclosed |
| EP-1076651-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | Aventis Pharma Deutschland GmbH (DE) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999057102-A1 | SUBSTITUTED SULPHONYL CYANAMIDES, METHOD FOR PRODUCING SAME AND THEIR USE AS MEDICAMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-11 | — | — | WO | disclosed |