Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719835 | 0.81 | LMNA (0.40) | KDM4EHSD17B10ALDH1A1TSHRLMNA | |
| SCHEMBL22637765 | 0.80 | NOTUM (0.33) | HCAR3HCAR2NOTUMKDM4EHSD17B10 | |
| SCHEMBL601435 | 0.80 | NOTUM (0.33) | NOTUMKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL3298133 | 0.80 | NOTUM (0.33) | NOTUMKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL28645320 | 0.79 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL1867900 | 0.77 | NOTUM (0.31) | NOTUMKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL4294216 | 0.77 | KMT2A (0.46) | KDM4EHSD17B10ALDH1A1TSHRLMNA | |
| SCHEMBL22637468 | 0.76 | KDM4A (0.33) | HCAR3NOTUMKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30798629 | 0.75 | NOTUM (0.45) | HCAR2NOTUMKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1864413 | 0.74 | ALDH1A1 (0.32) | NOTUMKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138791-A1 | EP2 ANTAGONIST | 小野薬品工業株式会社 | 2022-06-30 | — | — | WO | disclosed |
| EP-3157938-B1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECH PTY LTD (AU) | 2022-03-16 | — | — | EP | disclosed |
| US-20210387161-A1 | APPARATUS AND METHOD FOR PRODUCING FILMS OF POROUS COORDINATION POLYMERS BY FLOW OF REAGENTS | MATRIX SENSORS, INC. (US) | 2021-12-16 | — | — | US | disclosed |
| US-10768176-B2 | Hetero functional binding systems | ANTEO TECHNOLOGIES PTY LTD (AU) | 2020-09-08 | — | — | US | disclosed |
| WO-2020102616-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2020-05-21 | — | — | US | disclosed |
| US-20190255510-A1 | APPARATUS AND METHOD FOR PRODUCING FILMS OF POROUS COORDINATION POLYMERS BY FLOW OF REAGENTS | MATRIX SENSORS, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-20170173623-A1 | DEVICE AND METHOD FOR PRODUCING COATINGS OF POROUS COORDINATION POLYMERS BY FLOW OF REAGENTS | MATRIX SENSORS, INC. (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170115285-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECHNOLOGIES PTY LTD (AU) | 2017-04-27 | — | — | US | disclosed |
| EP-3157938-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | Anteo Technologies Pty Ltd. (AU) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015192183-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECHNOLOGIES PTY LTD (AU) | 2015-12-23 | — | — | WO | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157076-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | HCAR3 1373/4885HCAR2 1881/4885NOTUM 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.