Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 12/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 12/20 | 0.40 |
| ▸ | CDK2 | P24941 | 12/20 | 0.40 |
| ▸ | CDK4 | P11802 | 8/20 | 0.39 |
| ▸ | CCND1 | P24385 | 8/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892206 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP1A2GAACCNE2 | |
| SCHEMBL13300574 | 0.84 | ABCG2 (0.52) | ALDH1A1KDM4ECYP1A2CYP3A4GPR35 | |
| SCHEMBL6782273 | 0.83 | CYP1A2 (0.41) | ALDH1A1KDM4ECYP1A2L3MBTL1ATM | |
| SCHEMBL1462482 | 0.82 | MEN1 (0.48) | ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7432239 | 0.82 | GPR35 (0.46) | ALDH1A1KDM4ECYP1A2GAAGPR35 | |
| SCHEMBL6775090 | 0.82 | CYP1A2 (0.43) | KDM4ECYP1A2GAACCNE2CCNE1 | |
| SCHEMBL6258779 | 0.81 | CSF1R (0.34) | ALDH1A1CYP1A2CCNE2CCNE1CDK2 | |
| SCHEMBL27721400 | 0.81 | NPC1 (0.41) | ALDH1A1KDM4ECYP1A2GAACCNE2 | |
| SCHEMBL6184029 | 0.81 | HIF1A (0.40) | GPR35 | |
| SCHEMBL6182655 | 0.81 | GPR35 (0.39) | ALDH1A1KDM4EGAAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012733-A9 | COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES RESPONSIVE TO ANTIANGIOGENETIC THERAPY | NEUROSEARCH AS (DK) | 2005-03-10 | — | — | WO | claimed |