Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252866 | 0.83 | ALDH1A1 (0.68) | HRH4L3MBTL1SCD5NPC1MAPT | |
| SCHEMBL6253982 | 0.81 | ALDH1A1 (0.57) | HRH4L3MBTL1MAPTCA12CA1 | |
| SCHEMBL6232921 | 0.80 | ALDH1A1 (0.66) | HRH4L3MBTL1CHRNA7CA12CA1 | |
| SCHEMBL6234648 | 0.80 | CHRNA7 (0.53) | HRH4L3MBTL1CHRNA7NPC1RAB9A | |
| SCHEMBL6254206 | 0.80 | CHRNA7 (0.53) | HRH4L3MBTL1CHRNA7NPC1RAB9A | |
| SCHEMBL6616703 | 0.79 | ALDH1A1 (0.51) | HRH4L3MBTL1CHRNA7RAB9ACA12 | |
| SCHEMBL6234089 | 0.78 | HRH4 (0.69) | HRH4L3MBTL1CHRNA7NPC1RAB9A | |
| SCHEMBL6231088 | 0.78 | L3MBTL1 (0.69) | HRH4L3MBTL1CHRNA7NPC1MAPT | |
| SCHEMBL4395877 | 0.76 | TPSAB1 (0.55) | HRH4L3MBTL1CA12CA1CA2 | |
| SCHEMBL13212972 | 0.74 | CA12 (0.71) | NPC1RAB9ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |