Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718367 | 0.91 | MAPT (0.44) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL6983628 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL17242666 | 0.83 | TSHR (0.45) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL14892862 | 0.79 | MAPT (0.44) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL17186886 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL5484250 | 0.76 | TSHR (0.44) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL2337048 | 0.76 | POLB (0.47) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL17186888 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL14893069 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRLMNAPOLB | |
| SCHEMBL25221130 | 0.74 | MAPT (0.36) | ALDH1A1MAPTTSHRLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |