Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232118 | 0.87 | HDAC3 (0.41) | CHRNA7POLBLMNAHDAC3HDAC1 | |
| SCHEMBL6231717 | 0.86 | LMNA (0.42) | POLBTRPA1LMNAL3MBTL1MAPT | |
| SCHEMBL6233653 | 0.82 | PIM1 (0.50) | PIM1MAPTEPHX2HTTRAB9A | |
| SCHEMBL6233494 | 0.81 | POLB (0.58) | CHRNA7POLBLMNAHDAC3HDAC1 | |
| SCHEMBL12178218 | 0.78 | KMT2A (0.48) | POLBL3MBTL1CYP1A2MAPTMEN1 | |
| SCHEMBL2091142 | 0.75 | L3MBTL1 (0.42) | CHRNA7POLBLMNAHDAC3HDAC1 | |
| SCHEMBL3173854 | 0.74 | HDAC3 (0.41) | HDAC3HDAC1HDAC2L3MBTL1MAPT | |
| SCHEMBL21190211 | 0.73 | TSHR (0.41) | LMNAL3MBTL1 | |
| SCHEMBL5539306 | 0.72 | RORC (0.38) | L3MBTL1MAPTEPHX2MEN1HTT | |
| SCHEMBL10104354 | 0.72 | MCHR1 (0.40) | PIM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530562-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | Central Glass Company, Limited (JP) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004022521-A1 | OPTICALLY ACTIVE 1-(FLUORO-,TRIFLUOROMETHYL-OR TRIFLUOROMETHOXY-SUBSTITUTED PHENYL)ALKYLAMINE N-MONOALKYL DERIVATIVES AND PROCESS FOR PRODUCING SAME | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-18 | — | — | WO | disclosed |