SCHEMBL62323

SCHEMBL62323

CO[Si](CCCOCC(O)CNCCN(CCC[Si](OC)(OC)OC)CC(O)COCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASR P41180 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.30
GRK3 P35626 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9927985 0.95 CASR (0.36) CASRKDM4EALDH1A1HTTLMNA
SCHEMBL14865800 0.94 CASR (0.32) CASR
SCHEMBL16298576 0.91 HTT (0.35) CASRKDM4EALDH1A1HTT
SCHEMBL9928041 0.91 HTT (0.35) CASRKDM4EALDH1A1HTT
SCHEMBL15218971 0.90 HTT (0.34) CASRHTT
SCHEMBL9928000 0.89 CASR (0.34) CASRKDM4EALDH1A1HTTLMNA
SCHEMBL61834 0.88 USP2 (0.37) CASRKDM4EALDH1A1HTTLMNA
SCHEMBL9928090 0.88 CASR (0.35) CASR
SCHEMBL9928085 0.88 CASR (0.35) CASR
SCHEMBL9928083 0.88 CASR (0.35) CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377191-B2 Surfactant-stabilized organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2013-02-19 US disclosed
US-8128748-B2 Aqueous two-component organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2012-03-06 US disclosed
US-20090240072-A1 Mixing Device for Liquids SIKA TECHNOLOGY AG (CH) 2009-09-24 US disclosed
US-20090053411-A1 Surfactant-stabilized organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2009-02-26 US disclosed
US-20080314518-A1 Aqueous two-component organoalkoxysilane composition SUTTER JOLANDA 2008-12-25 US disclosed
US-20070190345-A1 Aqueous two-component organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053411-A1 Surfactant-stabilized organoalkoxysilane composition TST, STS, SMURF1 CASR 3624/4885KDM4E 4464/4885ALDH1A1 4417/4885
US-20090240072-A1 Mixing Device for Liquids SAMM50, CUL5, UBE3A CASR 3189/4885KDM4E 4664/4885ALDH1A1 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.