SCHEMBL6232708

SCHEMBL6232708

CO[Si](CCC(Cl)C(=O)O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6518679 0.85
SCHEMBL6519083 0.82 CA1 (0.33)
SCHEMBL3779655 0.77 GABRR1 (0.46) TBXAS1LMNA
SCHEMBL6344840 0.72 LDHA (0.33) TBXAS1LMNA
SCHEMBL7764310 0.72 LMNA (0.30) LMNA
SCHEMBL21066685 0.72 FOLH1 (0.50)
SCHEMBL7291121 0.71
SCHEMBL2193910 0.71 LMNA (0.50) TBXAS1LMNA
SCHEMBL3915323 0.70 CA1 (0.30)
SCHEMBL28429179 0.69 BLM (0.47) TBXAS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050229324-A1 Process and auxiliaries for the treatment of organically tanned leather TFL LEDERTECHNIK GMBH (DE) 2005-10-20 US disclosed
EP-1517999-A1 PROCESS AND AUXILIARIES FOR THE TREATMENT OF ORGANICALLY TANNED LEATHER TFL Ledertechnik GmbH (DE) 2005-03-30 EP disclosed
WO-2004003238-A1 PROCESS AND AUXILIARIES FOR THE TREATMENT OF ORGANICALLY TANNED LEATHER TFL LEDERTECHNIK GMBH (DE) 2004-01-08 WO disclosed