SCHEMBL623274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL623263	1.00	KDM4E (0.49)	KDM4EALDH1A1ALOX15KMT2AHSD17B10
	SCHEMBL622875	0.90	HSD17B10 (0.53)	KDM4EALDH1A1ALOX15KMT2AHSD17B10
	SCHEMBL622874	0.90	HSD17B10 (0.53)	KDM4EALDH1A1ALOX15KMT2AHSD17B10
	SCHEMBL622519	0.85	ALDH1A1 (0.51)	ALDH1A1KMT2AHSD17B10ELOVL1LMNA
	SCHEMBL623232	0.84	ACACB (0.51)	KDM4EALDH1A1ALOX15KMT2AHSD17B10
	SCHEMBL623231	0.84	ACACB (0.51)	KDM4EALDH1A1ALOX15KMT2AHSD17B10
	SCHEMBL623690	0.84	POLB (0.51)	KDM4EALDH1A1KMT2AHSD17B10ELOVL1
	SCHEMBL624188	0.83	MAPT (0.46)	KDM4EALDH1A1KMT2AHSD17B10ELOVL1
	SCHEMBL623234	0.82	ELOVL1 (0.51)	KDM4EKMT2AHSD17B10ELOVL1HPGD
	SCHEMBL624486	0.80	THRA (0.45)	KDM4EALDH1A1KMT2AELOVL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.