Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837435 | 0.94 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7768342 | 0.90 | CHRM3 (0.48) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL22791958 | 0.89 | BTK (0.45) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL30105719 | 0.86 | HTR1A (0.41) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL2014741 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL31198180 | 0.80 | POLB (0.58) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL18491364 | 0.79 | MOK (0.55) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL18998868 | 0.79 | ABL1 (0.44) | KDM4EALDH1A1BTK | |
| SCHEMBL6273594 | 0.77 | ALDH1A1 (0.57) | KDM4EALDH1A1MEN1HTTKMT2A | |
| SCHEMBL28627643 | 0.76 | EGFR (0.57) | KDM4EALDH1A1MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292270-B1 | Oxidative Dyeing Agent comprising 2-Hydroxy-5-Aminobenzyl-Piperazine as Developer | HENKEL KGAA (DE) | 2005-04-20 | — | — | EP | disclosed |
| EP-1292270-A1 | OXIDATION DYEING AGENT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-03-19 | — | — | EP | disclosed |