SCHEMBL7768342

SCHEMBL7768342

CC(=O)Nc1ccc(O)c(CN2CCNCC2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
ABL1 P00519 2/20 0.45
CYP3A4 P08684 1/20 0.45
BCR P11274 1/20 0.45
MKNK1 Q9BUB5 1/20 0.45
MKNK2 Q9HBH9 1/20 0.45
CHEK1 O14757 1/20 0.44
AURKA O14965 1/20 0.44
DAPK3 O43293 1/20 0.44
JAK2 O60674 1/20 0.44
PRKD3 O94806 1/20 0.44
PAK4 O96013 1/20 0.44
NTRK1 P04629 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
CSF1R P07333 1/20 0.44
RET P07949 1/20 0.44
IGF1R P08069 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232831 0.90 KDM4E (0.52) KDM4EALDH1A1BTKGAATSHR
SCHEMBL28837435 0.88 KDM4E (0.61) KDM4EALDH1A1GAATSHRMEN1
SCHEMBL15785524 0.84 LMNA (0.50) CHRM3KDM4EALDH1A1ABL1CYP3A4
SCHEMBL22791958 0.80 BTK (0.45) KDM4EALDH1A1BTKMEN1HTT
SCHEMBL30105719 0.77 HTR1A (0.41) KDM4EALDH1A1BTKGAATSHR
SCHEMBL11926135 0.77 CHRM3 (0.69) CHRM3KDM4EALDH1A1BTKTSHR
SCHEMBL2014741 0.77 KDM4E (0.61) KDM4EALDH1A1CYP3A4GAAMEN1
SCHEMBL22425608 0.76 LMNA (0.61) KDM4EALDH1A1TSHRHTTPOLB
SCHEMBL31198180 0.75 POLB (0.58) KDM4EALDH1A1CYP3A4TSHRMEN1
SCHEMBL18491364 0.74 MOK (0.55) KDM4EALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001097763-A2 OXIDATION DYEING AGENT CONTAINING 2-HYDROXY-5-AMINOBENZYL PIPERAZINES HENKEL KGAA (DE) 2001-12-27 WO disclosed