SCHEMBL28837435

SCHEMBL28837435

CC(=O)Nc1ccc(O)c(CN2CCCC2)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
ALDH1A1 P00352 2/20 0.61
TSHR P16473 2/20 0.55
GAA P10253 2/20 0.55
ACHE P22303 2/20 0.54
GFER P55789 1/20 0.52
CACNA1B Q00975 1/20 0.52
MOK Q9UQ07 1/20 0.52
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 1/20 0.48
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232831 0.94 KDM4E (0.52) KDM4EALDH1A1TSHRGAAACHE
SCHEMBL2014741 0.89 KDM4E (0.61) KDM4EALDH1A1GAAACHEGFER
SCHEMBL7768342 0.88 CHRM3 (0.48) KDM4EALDH1A1TSHRGAAMOK
SCHEMBL6273594 0.84 ALDH1A1 (0.57) KDM4EALDH1A1TSHRGAAGFER
SCHEMBL22791958 0.83 BTK (0.45) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5610627 0.81 CACNA1B (0.63) TSHRGAACACNA1BKMT2AMAPT
SCHEMBL30105719 0.81 HTR1A (0.41) KDM4EALDH1A1TSHRGAAMEN1
SCHEMBL27481931 0.79 ACHE (0.56) KDM4EALDH1A1TSHRGAAACHE
SCHEMBL334483 0.79 L3MBTL1 (0.67) ALDH1A1TSHRGAAACHEGFER
SCHEMBL20922005 0.79 KDM4E (0.56) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114878540-A Derivatization reagents, kits and methods for detecting nerve agents 中国人民解放军军事科学院军事医学研究院 2022-08-09 CN disclosed