Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229299 | 0.94 | NPC1 (0.36) | NPC1RAB9AHPGDMAPTGFER | |
| SCHEMBL6232864 | 0.83 | BRD4 (0.32) | — | |
| SCHEMBL6231406 | 0.74 | ABL1 (0.39) | NPC1RAB9AADORA3SYKAURKB | |
| SCHEMBL6235387 | 0.69 | ABL1 (0.35) | NPC1RAB9AMAPTABL1ABCB1 | |
| SCHEMBL6232128 | 0.68 | PTAFR (0.33) | NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7105430 | 0.64 | S1PR1 (0.38) | S1PR1 | |
| SCHEMBL23483176 | 0.64 | ALDH1A1 (0.55) | NPC1RAB9AMAPTALDH1A1HSP90AA1 | |
| SCHEMBL7106833 | 0.64 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL27970344 | 0.64 | ALDH1A1 (0.43) | NPC1RAB9AHPGDMAPTALDH1A1 | |
| SCHEMBL11096260 | 0.62 | ABL1 (0.76) | NPC1RAB9AMAPTSYKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |