Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232855 | 0.83 | NPC1 (0.39) | — | |
| SCHEMBL6229299 | 0.78 | NPC1 (0.36) | PTGS2 | |
| SCHEMBL15163552 | 0.70 | BRD4 (0.34) | BRD4CREBBPAPPPTGS2 | |
| SCHEMBL6232128 | 0.68 | PTAFR (0.33) | BRS3 | |
| SCHEMBL6381811 | 0.67 | MEN1 (0.33) | KCNH2 | |
| SCHEMBL27816404 | 0.66 | EPHX1 (0.34) | BRD4CREBBPKCNH2EPHX1EPHX2 | |
| SCHEMBL7112128 | 0.66 | UCHL3 (0.32) | — | |
| SCHEMBL7105430 | 0.64 | S1PR1 (0.38) | — | |
| SCHEMBL7110309 | 0.64 | UCHL3 (0.37) | — | |
| SCHEMBL27795507 | 0.64 | BRD4 (0.32) | BRD4CREBBPEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |