Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232855 | 0.94 | NPC1 (0.39) | NPC1RAB9AHTR2AHTR2CHTR2B | |
| SCHEMBL6232864 | 0.78 | BRD4 (0.32) | PTGS2 | |
| SCHEMBL6231406 | 0.70 | ABL1 (0.39) | NPC1RAB9ASYKAURKBINCENP | |
| SCHEMBL6235387 | 0.68 | ABL1 (0.35) | NPC1RAB9AABL1ABCB1BCR | |
| SCHEMBL11096260 | 0.61 | ABL1 (0.76) | NPC1RAB9ASYKAURKBINCENP | |
| SCHEMBL11096265 | 0.61 | ABL1 (0.58) | NPC1RAB9AABL1ABCB1BCR | |
| SCHEMBL19681496 | 0.61 | ALDH1A1 (0.52) | NPC1RAB9AHTR2AHTR2CHTR2B | |
| SCHEMBL6319062 | 0.60 | ABL1 (0.57) | NPC1RAB9AABL1ABCB1BCR | |
| SCHEMBL7150733 | 0.60 | HDAC4 (0.70) | NPC1RAB9AABL1ABCB1BCR | |
| SCHEMBL27970344 | 0.60 | ALDH1A1 (0.43) | NPC1RAB9AHTR2CABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |