Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235078 | 0.92 | CTSK (0.48) | TAS1R3TAS1R1TSHRCTSKCYP1A2 | |
| SCHEMBL4048294 | 0.88 | ALDH1A1 (0.37) | TAS1R3TAS1R1TSHRMCHR1CYP1A2 | |
| SCHEMBL6274440 | 0.88 | CTSK (0.48) | CTSKALDH1A1KMT2A | |
| SCHEMBL4045150 | 0.88 | CTSK (0.44) | CTSKLMNAALDH1A1KMT2A | |
| SCHEMBL4038812 | 0.86 | CTSK (0.54) | CTSK | |
| SCHEMBL4039713 | 0.86 | CTSK (0.45) | CTSK | |
| SCHEMBL4042617 | 0.85 | CTSK (0.46) | TAS1R3TAS1R1CTSK | |
| SCHEMBL4040752 | 0.85 | CTSK (0.54) | CTSKALDH1A1 | |
| SCHEMBL4044103 | 0.85 | CTSK (0.42) | TAS1R3TAS1R1CTSKKMT2A | |
| SCHEMBL4042168 | 0.85 | CTSK (0.42) | CTSKLMNASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |