Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372873 | 0.76 | FGFR1 (0.35) | ALDH1A1USP2LMNAHTTKMT2A | |
| SCHEMBL55693 | 0.73 | ALDH1A1 (0.44) | CYP1A2CYP2C9ALDH1A1LMNAKMT2A | |
| SCHEMBL7363335 | 0.72 | FGFR1 (0.36) | ALDH1A1LMNAHTTKMT2AHPGD | |
| SCHEMBL6233928 | 0.72 | TUBB4A (0.40) | CYP1A2LMNAHIF1ATSHRMAPT | |
| SCHEMBL6232025 | 0.72 | MAPK1 (0.40) | CYP1A2ALDH1A1LMNAHIF1AHPGD | |
| SCHEMBL6237667 | 0.71 | CYP1A2 (0.41) | CYP1A2CYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL11375853 | 0.69 | XDH (0.39) | CYP1A2CYP2C9ABL1ALDH1A1FGFR1 | |
| SCHEMBL31024286 | 0.69 | BRD4 (0.38) | CYP1A2CYP2C9ALDH1A1LMNAHTT | |
| SCHEMBL24113223 | 0.68 | NR4A2 (0.48) | ABL1ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL31568995 | 0.68 | MAPT (0.44) | CYP1A2CYP2C9ABL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896517-B1 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | SCHICK MARY P (US) | 2005-05-25 | — | — | EP | disclosed |
| US-5861142-A | DERMATOLOGY AND GROWTH OF HAIR NAILS AND SKIN | SCHICK MARY PICHLER (US) | 1999-01-19 | — | — | US | disclosed |