Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261792 | 1.00 | PTPRZ1 (0.43) | PTPRZ1MAOBMAOAPTPN1PTPN2 | |
| SCHEMBL6256021 | 0.89 | PTPRZ1 (0.42) | PTPRZ1PTPN1PTPN2PTPN7PPARD | |
| SCHEMBL6232104 | 0.89 | PTPRZ1 (0.42) | PTPRZ1PTPN1PTPN2PTPN7PPARD | |
| SCHEMBL6236427 | 0.85 | MAOB (0.46) | MAOBMAOA | |
| SCHEMBL6235284 | 0.84 | PTPRZ1 (0.37) | PTPRZ1PTPN1 | |
| SCHEMBL6231277 | 0.81 | PTPRZ1 (0.41) | PTPRZ1PPARDCTSA | |
| SCHEMBL6232919 | 0.81 | PTPRZ1 (0.44) | PTPRZ1MAOBMAOAPTPN1PTPN2 | |
| SCHEMBL6236909 | 0.79 | NTRK1 (0.41) | PTPRZ1LMNACTSA | |
| SCHEMBL6231782 | 0.78 | MAOB (0.43) | MAOBMAOAPPARDNR1H4LMNA | |
| SCHEMBL6235743 | 0.75 | PDCD1 (0.39) | PTPRZ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |