Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230535 | 0.87 | CD274 (0.46) | MAOBMAOABCHEMEN1KMT2A | |
| SCHEMBL6261792 | 0.85 | PTPRZ1 (0.43) | MAOBMAOA | |
| SCHEMBL6232917 | 0.85 | PTPRZ1 (0.43) | MAOBMAOA | |
| SCHEMBL6237847 | 0.84 | BCHE (0.54) | BCHEMEN1KMT2A | |
| SCHEMBL6237852 | 0.84 | BCHE (0.54) | BCHEMEN1KMT2A | |
| SCHEMBL6231782 | 0.84 | MAOB (0.43) | MAOBMAOAALDH1A1MEN1KMT2A | |
| SCHEMBL6233689 | 0.80 | CD274 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6233776 | 0.78 | CD274 (0.45) | MEN1KMT2A | |
| SCHEMBL6236432 | 0.78 | BCHE (0.46) | S1PR1PRKXACVR1S1PR5ALDH1A1 | |
| SCHEMBL6233814 | 0.76 | FFAR4 (0.45) | ALDH1A1BCHEMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |