Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235284 | 0.89 | PTPRZ1 (0.37) | PTPRZ1FFAR4 | |
| SCHEMBL6231277 | 0.86 | PTPRZ1 (0.41) | NTRK1CSF1RNTRK2PTPRZ1CTSA | |
| SCHEMBL6231703 | 0.86 | LMNA (0.53) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6231706 | 0.86 | LMNA (0.53) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6235743 | 0.85 | PDCD1 (0.39) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6256021 | 0.85 | PTPRZ1 (0.42) | NTRK1CSF1RNTRK2PTPRZ1CTSA | |
| SCHEMBL6232104 | 0.85 | PTPRZ1 (0.42) | NTRK1CSF1RNTRK2PTPRZ1CTSA | |
| SCHEMBL6236884 | 0.80 | SMN1; SMN2 (0.46) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6276107 | 0.80 | MTNR1A (0.46) | CSF1RLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6235475 | 0.80 | MTNR1A (0.46) | CSF1RLMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |