Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577670 | 0.83 | SLC6A3 (0.65) | ALKBH5PDPK1FFAR1ALDH1A1SLC6A3 | |
| SCHEMBL29369594 | 0.83 | CYSLTR2 (0.59) | ALKBH5PDPK1FFAR1ALDH1A1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL2577794 | 0.81 | SLC6A3 (0.62) | ALKBH5PDPK1FFAR1ALDH1A1SLC6A3 | |
| SCHEMBL29664591 | 0.79 | KMT2A (0.53) | ALKBH5PDPK1FFAR1ALDH1A1CYSLTR2 | |
| SCHEMBL23215107 | 0.79 | KMT2A (0.53) | ALKBH5PDPK1FFAR1ALDH1A1CYSLTR2 | |
| SCHEMBL7525590 | 0.79 | SLC6A3 (0.51) | SLC6A3CYP2D6CYP2C19LMNA | |
| SCHEMBL6232709 | 0.77 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL29451204 | 0.77 | SLC6A3 (0.42) | ALDH1A1SLC6A3LMNA | |
| SCHEMBL6691161 | 0.75 | SLC6A3 (0.56) | ALKBH5PDPK1ALDH1A1SLC6A3CYP2D6 | |
| SCHEMBL20544211 | 0.74 | PDPK1 (0.60) | ALKBH5PDPK1FFAR1ALDH1A1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282397-B1 | USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT | OREAL (FR) | 2005-05-04 | — | — | EP | claimed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | claimed |
| EP-0858319-B1 | USE OF CARBOXYLIC ACIDS HAVING A SULPHUR FUNCTION FOR PROMOTING SKIN EXFOLIATION OR STIMULATING EPIDERMAL REGENERATION | OREAL (FR) | 2003-07-23 | — | — | EP | claimed |
| US-6153649-A | Use of carboxylic acids having a sulphur function for promoting skin exfoliation or stimulating epidermal regeneration | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | L'OREAL (FR) | 2004-02-26 | — | — | US | disclosed |
| EP-0713105-B1 | Composition for optical materials and use thereof | MITSUI CHEMICALS INC (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6153649-A | Use of carboxylic acids having a sulphur function for promoting skin exfoliation or stimulating epidermal regeneration | L'OREAL (FR) | 2000-11-28 | — | — | US | disclosed |
| US-5756766-A | Composition for optical materials and use thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5652321-A | Composition for optical materials and use thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0713105-A2 | Composition for optical materials and use thereof | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040037856-A1 | Use of compounds containing a thio-ether, sulphoxide or sulphone function as cosmetic anti-pollution agent | TST, STS, MPST | ALKBH5 1831/4885PDPK1 2863/4885FFAR1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.