Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.42 |
| ▸ | CTSA | P10619 | 7/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.41 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.41 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.41 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236773 | 0.93 | CTSA (0.41) | CD274CTSAPDCD1 | |
| SCHEMBL6257115 | 0.91 | CTSA (0.39) | CD274CTSAPDCD1 | |
| SCHEMBL6257119 | 0.91 | CTSA (0.39) | CD274CTSAPDCD1 | |
| SCHEMBL6233511 | 0.86 | CTSA (0.42) | CD274CTSAPDCD1 | |
| SCHEMBL6233776 | 0.86 | CD274 (0.45) | CD274PDCD1 | |
| SCHEMBL6236884 | 0.84 | SMN1; SMN2 (0.46) | CTSAGUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL6235441 | 0.84 | GPBAR1 (0.40) | CD274CTSA | |
| SCHEMBL6252802 | 0.84 | GPBAR1 (0.40) | CD274CTSA | |
| SCHEMBL6235514 | 0.83 | CD274 (0.40) | CD274CTSAPDCD1GUCY1B2GUCY1A2 | |
| SCHEMBL6232098 | 0.80 | CD274 (0.40) | CD274CTSAPDCD1GUCY1B2GUCY1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |