Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 13/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233776 | 0.90 | CD274 (0.45) | KMT2ACD274PDCD1 | |
| SCHEMBL6231277 | 0.87 | PTPRZ1 (0.41) | CTSACD274PDCD1 | |
| SCHEMBL6257119 | 0.87 | CTSA (0.39) | CTSACD274PDCD1 | |
| SCHEMBL6257115 | 0.87 | CTSA (0.39) | CTSACD274PDCD1 | |
| SCHEMBL6233373 | 0.86 | CD274 (0.42) | CTSACD274PDCD1 | |
| SCHEMBL6236773 | 0.82 | CTSA (0.41) | CTSAKMT2ACD274PDCD1 | |
| SCHEMBL6253469 | 0.79 | CTSA (0.42) | CTSAKMT2AMAOBCD274PDCD1 | |
| SCHEMBL6237287 | 0.79 | CTSA (0.42) | CTSAKMT2AMAOBCD274PDCD1 | |
| SCHEMBL6233515 | 0.78 | BCHE (0.41) | KMT2AMAOBCD274PDCD1 | |
| SCHEMBL6230535 | 0.78 | CD274 (0.46) | CTSAKMT2AMAOBCD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |