Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233779 | 0.90 | CD274 (0.49) | BCHECD274KMT2ANPSR1KDM4E | |
| SCHEMBL6231278 | 0.87 | PTPRZ1 (0.41) | BCHECD274KMT2AMEN1 | |
| SCHEMBL6233378 | 0.86 | CD274 (0.43) | CD274KMT2ATDP1KDM4EPDCD1 | |
| SCHEMBL6236777 | 0.82 | SMN1; SMN2 (0.46) | CD274KMT2ATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL6233511 | 0.78 | CTSA (0.42) | CD274KMT2AMAOBPDCD1 | |
| SCHEMBL6230537 | 0.78 | BCHE (0.52) | BCHECD274KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6237290 | 0.78 | TMEM97 (0.36) | CD274KMT2AMEN1 | |
| SCHEMBL6232926 | 0.76 | PTPRZ1 (0.42) | BCHECD274HTR2AKMT2AKDM4E | |
| SCHEMBL6271288 | 0.76 | PTPRZ1 (0.38) | CD274PDCD1 | |
| SCHEMBL6234948 | 0.76 | PTPRZ1 (0.38) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |