Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233378 | 0.93 | CD274 (0.43) | CD274KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6235445 | 0.90 | SMN1; SMN2 (0.44) | SMN1; SMN2CD274KMT2AGPBAR1MEN1 | |
| SCHEMBL6235523 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2CD274KMT2AGPBAR1MEN1 | |
| SCHEMBL6231785 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1LMNAKDM4E | |
| SCHEMBL6233374 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2CD274KMT2AMEN1LMNA | |
| SCHEMBL6233515 | 0.82 | BCHE (0.41) | SMN1; SMN2CD274KMT2AMEN1LMNA | |
| SCHEMBL6233779 | 0.82 | CD274 (0.49) | SMN1; SMN2CD274KMT2AMEN1LMNA | |
| SCHEMBL6232102 | 0.80 | CTSA (0.44) | CD274 | |
| SCHEMBL6236773 | 0.80 | CTSA (0.41) | SMN1; SMN2CD274KMT2AGPBAR1PDCD1 | |
| SCHEMBL6236888 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |