Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233515 | 0.90 | BCHE (0.41) | CD274BCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6230537 | 0.88 | BCHE (0.52) | CD274BCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6233378 | 0.86 | CD274 (0.43) | CD274KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6231278 | 0.85 | PTPRZ1 (0.41) | CD274BCHEKMT2AMEN1 | |
| SCHEMBL6235980 | 0.84 | SMN1; SMN2 (0.59) | BCHEKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6239778 | 0.83 | BCHE (0.65) | BCHEKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6240567 | 0.82 | BCHE (0.64) | BCHEKMT2AMEN1MAPK1 | |
| SCHEMBL6236777 | 0.82 | SMN1; SMN2 (0.46) | CD274KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL6236432 | 0.79 | BCHE (0.46) | BCHEKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6233816 | 0.79 | SLC2A1 (0.51) | CD274BCHEKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |