Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929054 | 0.70 | ALDH1A1 (0.38) | KDM4EPOLBSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1912823 | 0.68 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL5929010 | 0.65 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL5929119 | 0.64 | CYP2A13 (0.43) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL1912824 | 0.64 | PTGER4 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL5929075 | 0.62 | PDCD1 (0.31) | POLB | |
| SCHEMBL650433 | 0.61 | CRHR1 (0.36) | ALDH1A1 | |
| SCHEMBL5928948 | 0.61 | OPRK1 (0.40) | KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL5929191 | 0.60 | KDM4E (0.52) | KDM4EPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7081245 | 0.60 | TAAR1 (0.40) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007087-A2 | SUBSTITUTED (HETEROCYCLOALKYL)METHYL AZOLE DERIVATIVES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |